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Platelet-rich Plasma (PRP)

Platelet rich plasma is a preparation of highly concentrated platelets above what is normally contained in our blood. Platelets are cells that are found in your blood that contains thousands of growth factors and proteins that stimulate tissue healing and wound repair. Plasma is the liquid portion of blood that consists of water and other important substances that support healing ; it provides a fluid medium for cells to circulate.

How does PRP work?

The growth factors, proteins and molecules released by the platelets have been shown to stimulate repair cells to go to areas of injury, promote tissue building and stimulate blood vessel formation. They have also been shown to decrease inflammation and cartilage degradation.

How is PRP made?

Platelet rich plasma is produced by first collecting a sample of your blood (about 60 mL or four tablespoons). The next step involves a centrifugation process where the patient's whole blood is separated to it's different cellular components and the platelets are concentrated above baseline levels, typically 2-6 times more or higher. The whole process takes about 20-30 mins and is performed in our laboratory where a strict sterile process is observed to keep the samples safe and clean. The final PRP product is then collected in a syringe ready for injection.

What Orthopedic Conditions can be treated with PRP?

  • Osteoarthritis
  • Tendon degeneration or tendon tear
  • Ligament sprain or tear
  • Soft tissue injuries from sports
  • Degenerative disc disease in the spine
  • Nerve injuries

What are the Possible side effects of a PRP injection?

Side effects are the same side effects associated with other injections like pain from the injection site, bleeding, infection, and nerve injury. The safety of PRP have been proven in many studies and is associated with minimal to no risks since it uses the patient's own blood.

Cell based Therapies

BIOEVOLVE offers two different kinds of cell based therapies that can be used to treat orthopedic conditions: bone marrow-derived cells and adipose-derived cells. These treatments are minimally invasive,non-surgical treatments performed in a doctor's clinic using only local anesthesia.

Bone Marrow Aspiration Concentrate (BMAC)

Bone marrow-derived cells are collected from the back of the pelvic bone. The marrow contains mesenchymal stem cells which have the ability to renew themselves and differentiate into bone, tendon, cartilage and muscle cells. BMAC also contains important therapeutic cells, growth factors and proteins that stimulate the body's natural ability to improve circulation, decrease inflammation and heal injured tissues.

Microfragmented Adipose Tissue Cells (MFAT)

Adipose-derived cells are collected from a fat sample from the buttock, waist, or abdomen. There is minimal manipulation of the tissue with no enzymatic digestion or addition of other biological or pharmacological agents. Fat or adipose tissue is rich in healing cells like mesenchymal stem cells or MSCs, growth factors and other proteins that can assist in healing tissues.

The cells derived from bone marrow and adipose (fat) tissue produce molecules that direct other healing cells to go the injured region to form new blood vessels, stimulate other stem cells, and stimulate proliferation of other cells to produce healthy tissue.

The U.S. Food and Drug Administration (FDA) does not allow physicians to use stem cells from another person without FDA approval. Therefore, at Bioevolve we do NOT use cells derived from another person. This includes embryonic stem cells or donor stem cells derived from amniotic fluid or other birth tissue products.

With these cells, there is a risk of disease transmission or immune reaction. The donor tissues are sterilized to minimize the risk of disease transmission, but living stem cells do not survive the sterilization process therefore no live stem cells have been found in these products.

We only use your own cells derived from your own bone marrow or adipose (fat) tissue.